An AI-powered platform backed by deep science

Cleerly is a revolutionary cardiac care platform that leverages AI technology to analyze and characterize plaque, calculate stenosis and detect likely ischemia in specific vessels.


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Cleerly uses proprietary and FDA-cleared machine learning algorithms to non-invasively measure atherosclerosis (plaque), stenosis, and likelihood of ischemia using coronary computed tomography angiography (CCTA) studies.

Our machine-learning AI generates a 3D model of the patient’s coronary arteries, identifies their lumen and vessel walls, locates and measures stenoses, while quantifying and categorizing plaque.1 Cleerly ISCHEMIA’s algorithm uses measurements based on invasive FFR data to determine the likelihood of vessel-level ischemia.2

These sets of quantitative measurements are presented in a comprehensive report to support providers in efficient diagnosis and personalized patient treatment. Physicians can also review results in depth via our interactive web platform.

Cleerly’s analyses are grounded in science, based on over 10 million images from over 40,000 patients gathered over a 15-year-period in landmark, multi-center clinical trials.3 In a number of clinical studies, Cleerly has shown to be comparable to invasive gold standards, including IVUS4, NIRS5, FFR6, OCT7 and QCA.8

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Personalized analysis and treatment

Cleerly’s comprehensive coronary plaque, stenosis and ischemia analyses provides actionable insights for physicians that go beyond the CCTA with detailed vessel-by-vessel evaluation.

Our analyses may also:

  • Enable earlier diagnosis and facilitate precision treatment.9, 10
  • Help inform patient’s eligibility for care pathways like invasive coronary angiography.11
  • Streamline CCTA evaluation process.
  • Positively influence patient adherence to physician-recommended treatment plans.

Measurable & actionable insights

Cleerly Reports include an interactive, web-based summary and details of our AI-based plaque, stenosis and ischemia analysis to help providers translate clinical data for personalized CAD diagnosis and treatment.

Provider reports include an interactive, web-based summary of findings and details on the total amount and type of plaque, severity of stenoses, and likelihood of ischemia within individual vessels.

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Efficient workflows

CCTA uploads for Cleerly analysis can be done a number of ways, including through direct upload, the Nuance Powershare network, intelerad Inteleshare, and Cleerly Proxy. Cleerly Proxy is a cloud-based solution with minimal onsite footprint that integrates into existing hospital, health system, and practice workflows.

Average Cleerly processing time is 1 hour, 20 minutes* with <2% rejection rates within two hours*, and can be received via email, DICOM PDF, DICOM SC or our web portal.


Download the Proxy Data Sheet


*During standard working hours Monday to Friday until 6PM EST

Request your Cleerly demo

Contact us for a one-on-one software demonstration with a Cleerly expert to see how bringing Cleerly’s AI‑driven CCTA analysis to your organization can empower you to provide personalized treatment decisions for your patients.

Request a Demo